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KMID : 0191119990140060679
Journal of Korean Medical Science
1999 Volume.14 No. 6 p.679 ~ p.681
Macroamylasemia in a patient with acute appendicitis: a case report
Um JW
Kim KH/Kang MS/Choe JH/Bae JW/Hong YS/Suh SO/Kim YC/Whang CW/Kim SM
Abstract
Macroamylasemia is a condition of persistent, elevated serum amylase activity with no apparent clinical symptoms of a pancreatic disorder. In Korea, however, no such case has been reported to date. We report a case of a 17-year-old female diagnosed with macroamylasemia and acute appendicitis. One day earlier, she developed epigastric and right lower quadrant abdominal pain. She was characterized by high level of serum amylase, but normal lipase. Amylase isoenzyme analysis demonstrated increased fraction of salivary type and follow-up amylase level was persistently increased. Immunofixation disclosed the macroamylase binding with an immunoglobulin, consisting of IgA and kappa chain. The patient was treated by appendectomy, and the abdominal pain subsided.
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